What's new in Sim4Life.desktop
Sim4Life V8.0.1 is the latest version of our simulation platform for computational life science research, device design and optimization, and safety and electromagnetic compliance evaluations.
The highlights of Sim4Life V8.0.1:
- GPU/multi-GPU Support for Thermal Solver: multi-GPU support for its thermal solver, achieving a substantial 50× speed-up, and supports a wide array of NVIDIA GPU architectures,
including the cutting-edge Ada Lovelace architecture (e.g., RTX 4080).
- Generalized Multiport Simulations (Low Frequency EM, Thermal): extended support for multi-channel finite-difference time-domain (FDTD) solvers to low-frequency solvers,
our one-of-a-kind thermal solver, and linked simulations.
- New VULKAN Renderer for 3D Visualizations: new state-of-the-art VULKAN rendering engine. The next generation graphics and compute API provides high-efficiency,
cross-platform access to modern GPUs, allowing for superior rendering control, performance, and speed when visualizing highly complex scenarios (shading, transparency, number of elements).
- Generalized Activating Function: rapid prediction of neural recruitment with Generalized Activating Function (two orders of magnitude speedup).
- AI-Based Anatomical Model Generation: new updated AI image segmentation tools to generate best in class personalized anatomical head models.
- Modeling/Meshing Enhancements: streamlined process of defining and modifying surface patches with an interactive, step-by-step approach.
Version History
Sim4Life is frequently updated. Updates are cumulative, so when you use the most recent version of Sim4Life.desktop, it has all the latest features. You can see all the new features included with each release below.
- Maintenance release based on Sim4Life V8.0. The release includes bug fixes only.
- Multi-GPU support for the thermal solver.
- Generalized multiport simulations now supporting low-frequency EM and thermal solvers, in addition to FDTD.
- New VULKAN renderer for 3D visualizations.
- Rapid prediction of neural recruitment with Generalized Activating Function (two orders of magnitude speedup).
- Maintenance release based on Sim4Life V7.2.3. The release includes bug fixes only.
- Maintenance release based on Sim4Life V7.2.1. The release includes bug fixes only.
- Maintenance release based on Sim4Life V7.2. The release includes bug fixes only.
- Sim4Life Python Scripting: Sim4Life’s integration with JupyterLab together with the upgrade to Python V3.8.
- Exposures: handling of pulsed exposures throughout Sim4Life, e.g., as modulated sources in thermal and neuro simulations.
- IMAnalytics Suite V1.2: new goal-oriented high-level application processing interface (API) for fast in silico evaluation and comparison with in vitro measurements.
- New tools to convert multi-channel pTx coil array models into virtual observation points (VOPs) for real-time safety control.
- Ultra-obese Virtual Population (ViP) models: three morbidly obese versions of the adult models Ella and Fats added to the ViP library.
- Maintenance release based on Sim4Life V7.0.1. The release includes bug fixes only.
- Maintenance release based on Sim4Life V7.0. The release includes bug fixes only.
- Module T-NEURO: faster by >10x, a new axon model, and an improved neuroscience-guided user interface.
- IMAnalytics Suite V1.0: now includes a novel Test Field Diversity (TFD) method for in vitro measurements.
- Sim4Life and DASY8/6: numerical models created with DASY8/6 Module mmWave V3.0+ can now be directly imported - without cumbersome validation - for further in silico evaluation.
- New solver-enhanced phantoms: accurate simulations of body-mounted 5G NR FR2 devices as well as computation of over-the-air performance and absorbed power densities without limitations.
- Smaller file sizes: results from full-wave simulations can now be automatically compressed, resulting in massive savings of up to 20x in file size.
- Eddie cV3.1: a new high-quality posable human male anatomical phantom has been added to the Virtual Population library.
- Maintenance release based on Sim4Life V6.2.1. The release includes bug fixes only.
- Maintenance release based on Sim4Life V6.2.1. The release includes bug fixes only.
- NeuroRat V4.0: the first neuro-functionalized animal model for neuro-electrophysiology simulations that can be posed and features detailed nerve trajectories.
- 5G Transmitter Design and Evaluation: user-defined codebooks (incl. phase configuration uncertainty) as part of our Maximum
Exposure Optimizer, which now supports synchronized features with DASY6 Module mmWave and full compatibility with FDIS of IEC/IEEE 63195-1 and 63195-2.
- IP protection: effective collaboration while protecting intellectual properties (IP) of key active and passive components based on a unique Huygens source feature.
- New toolbox to generate implant routings for magnetic resonance imaging (MRI) safety evaluations.
- Maintenance release based on Sim4Life V5.2.1. The release includes bug fixes only.
- Maintenance release based on Sim4Life V5.2. The release includes bug fixes only.
- Octree-based Adaptive Meshing Engine: new, robust meshing engine to mesh highly complex surface-based structures such as the anatomical models of the Virtual Population.
- 5G Transmitter Design and Evaluation: enhanced with the Total Exposure Ratio (TER) evaluator that allows to assess the cumulative exposure of all frequency bands operating between 100kHz - 110GHz according to the latest draft of the IEC/IEEE standard series.
- Python 3: Sim4Life is now available with either a Python 2 or with a Python 3 distribution and API.
- IMAnalytics: now also supports Tier 2 evaluations by providing owners of the MRIxViP field library with a streamlined and reproducible workflow for extracting field data in customized regions of interest, with derivation of all statistics necessary for Tier 2 of ISO/TS 10974.
18 September 2019 (V5.0.1 release notes)
- Maintenance release based on Sim4Life V5.0. The release includes bug fixes only.
- Novel electromagnetics unstructured finite element method (FEM) low frequency solver suite: combined with mesher engines enable
the meshing of highly complex TCAD objects embedded in detailed anatomical environments such as the latest functionalized ViP
models.
- GUI performance boosts in V5.0, making simulations of complex neurostimulation applications an every-day task in Sim4Life.
- Features enhancements of our 5G Toolkit, GUI/usability extensions, HPC/GPU boosts, data analysis/post-processing
enhancements.
- Korean male Jeduk V3.1: new (neuro-)functionalized Virtual Population model.
- Coupled electromagnetic (EM) neuro multi-parameter optimization.
- Integration of the new Virtual Population (ViP) phantom Yoon-sun V4.0 that features neuro-functionalized nerve trajectories compatible with T-NEURO, modeled as splines and assigned nerve electrophysiology and neuroanatomy parameters.
- Robust Maximum Exposure algorithm for determining the largest power density of antenna arrays of any size on any arbitrary surface via a semi-analytical solver and five iterative optimization methods running in parallel
- SAPD algorithm: surface-average of power density using either norm or normal component of Poynting vector.
- New algorithm implementing Gamma dose comparison method.
- User-defined analysis pipelines allow saving postprocessing workflows.
- IMAnalytics v2: new features in Python Notebook, including normalization to B1 in slice and advanced plotting features
- Maintenance release based on Sim4Life V4.0. The release includes bug fixes only.
- Novel multi-parameter and multi-goal optimization framework.
- Full integration and support for the NIMBIX Cloud platform.
- Graphical visualization of the circuit networks for matching, tuning, and decoupling of multiport simulations.
- Parallelization/HPC support for coupled EM-neuron dynamics modeling.
- Maintenance release based on Sim4Life V3.4.2. The release includes bug fixes only.
11 September 2017 (V3.4.2 release notes)
- Maintenance release based on Sim4Life V3.4.1. The release includes bug fixes only.
- Maintenance release based on Sim4Life V3.4. The release includes bug fixes only.
- IMAnalytics Module:the unique solution for the comprehensive safety evaluation of implantable devices now shortening evaluation time from many weeks to just a few hours.
- Fastest Peak Spatial-Average SAR algorithm: highly efficient implementation of the IEEE/IEC62704-1 SAR averaging standard algorithm.
- Major speedup of the adaptive subgridding.
- New RCS (Radar Cross-Section) simulation/evaluation for large objects to calculate bi-static and mono-static RCS.
- Maintenance release based on Sim4Life V3.2.3. The release includes bug fixes only.
- Maintenance release based on Sim4Life V3.2.0. The release includes bug fixes only.
- New automated parametrization and sweeeping engine capable of performing all the tasks related to a given project (model generation, simulation, and analysis) in an independent environment.
- Novel adaptive subgridding algorithm which - in a fully automated manner - places an optimum arrangement of individual subgrids around any solid/mesh/CAD model, allowing for highest effectiveness in local mesh refinement.
- Unique and powerful toolbox to optimize and assess the performance of 5G solutions and demonstrate their compliance to international standards.
- Neuronal Dynamics Module extensions.
- Maintenance release based on Sim4Life V3.0.1. The release includes bug fixes only.
- New physics-based poser engine for posing anatomical models based on biomechanical finite element method (FEM) simulations, now available for all models of the Virtual Population, allows for more robust results with challenging postures.
- Finite-difference time-domain (FDTD) topological voxeler engine that is up to 20× faster than the old approach and achieves better results with coarser grids for discretization of complex/fine structures (>10× faster runtime for specific simulations).
- New solver: EM Low-Frequency Static Vector Potential Solver.
- New features for WPT applications: Coil wizard, surface current sources, a calculator for magnetic energy.
- Gradient Coil Designer allows MRI gradient coils to be designed for a given coil geometry and specifications.
- Maintenance release based on Sim4Life V2.2. The release includes bug fixes only.
- Finite-difference time-domain (FDTD) solver: Debye, Lorentz, Drude, and generic dispersion models (electric and magnetic) along with an improved dispersive parameter fitting tool.
- P-ACOUSTICS module is now multi-GPU accelerated. It now also features dedicated modeling tools, which allow quick and intuitive setup of complex transducer arrays.
- IMSAFE-G module for assessment of MRI safety of active implanted medical devices with respect to gradient-induced fields.
- State-of-the-art solver based on the mode-matching technique (MMT) combined with the generalized scattering matrix (GSM).
- MATCH module for determination of S-Parameters, fields, and port parameters has been improved and allows extraction of all results w/o resimulation.
- Fully posable, high-fidelity, 3D computable Virtual Population anatomical models.
- Subgrid EM-FDTD engine that locally resolves the model at extreme detail with reduced simulation times and computationally supports its accuracy.
- New neuronal dynamics module that embeds realistic neuronal dynamics simulations into the simulation flows (coupled EM-neuronal dynamics). Additional solvers address acoustics and biofluidics.
- Framework enhancements such as the concurrent handling of meshes and NURBS, an entirely new and user friendly Python API, and a Workbench for complex analysis and visualization pipelines.
- Modeling: New Center Line extraction tool, enhanced REMESH tool for mesh editing, Mesh Doctor for inspection of triangle surface meshes.
- Simulation: New user-defined EM-FDTD, EM-QS and Thermal sources.
- Analysis: Far Field sensor, Smith Chart plot, Histogram viewer.
- Extended Python API
1 August 2014 (V1.0)
Launch of our new revolutionary simulation platform Sim4Life V1.0. Sim4Life integrates computable human phantoms with the most powerful physics solvers and the most advanced tissue models to directly analyze biological real-world phenomena and complex technical devices in a validated biological and anatomical environment. Architected with high performance computing enabled solvers and the most intuitive GUI, Sim4Life enables accurate coupled multiphysics simulations and endless customization for accelerating R&D activities, designing and optimizing medical devices and treatments, assessing safety and efficacy, enriching personalized medicine strategies, conducting mechanistic research, reducing costs, and achieving regulatory compliance.
